GENETIC REGULATION OF RNA SPLICING IN HUMAN PANCREATIC ISLETS

Genetic regulation of RNA splicing in human pancreatic islets

Abstract Background Non-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk.For many loci, however, the mechanisms through which non-coding variants influence diabetes susceptibility are unknown.Resul

read more


Characterization of influenza A virus induced transposons reveals a subgroup of transposons likely possessing the regulatory role as eRNAs

Abstract Although many studies have observed genome-wide host transposon expression alteration volcano crisps during viral infection, the mechanisms of induction and the impact on the host remain unclear.Utilizing recently published influenza A virus (IAV) time series data and ENCODE functional genomics data, we characterized virus induced host dif

read more

Experimental and Numerical Study on the Characteristics of Motion and Load for a Floating Solar Power Farm under Regular Waves

Recently, the demand for floating solar power farms in lakes and coasts (rather than on land) has been increasing rapidly.It is important to develop a numerical analysis technique that considers environmental conditions to predict structural stability and accurate motion response while designing a floating hustler magazine t shirt solar power farm.

read more